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tenofovir disoproxil fumarate (Viread®)


Reference No. 1643

Publication date:
15/08/2013


Last review date:
30/08/2016

Appraisal information

tenofovir disoproxil fumarate (Viread®) 245 mg film-coated tablet
tenofovir disoproxil fumarate (Viread®) 33 mg/g granules
tenofovir disoproxil fumarate (Viread®) 204 mg film-coated tablet
tenofovir disoproxil fumarate (Viread®) 163 mg film-coated tablet
tenofovir disoproxil fumarate (Viread®) 123 mg film-coated tablet


Company: Gilead Sciences Ltd
BNF category: Infections
NMG meeting date: 19/06/2013
AWMSG meeting date: 17/07/2013
   
   
Submission Type: Limited Submission
Status: Recommended
Advice No: 2213
Ministerial ratification: 14/08/2013

Current Progress


Submission
received
NMG
meeting
AWMSG
meeting
Ministerial
Ratification

AWMSG advice

Tenofovir disoproxil (as fumarate) (Viread®) film-coated tablets are recommended as an option for use within NHS Wales in combination with other antiretroviral medicinal products for the treatment of HIV-1-infected adolescent and paediatric patients, with nucleoside reverse transcriptase inhibitor (NRTI) resistance or toxicities precluding the use of first line agents, aged 12 to < 18 years (245 mg tablets) and aged 6 to < 12 years who weigh from 17 kg to less than 22 kg (123 mg tablets), 22 kg to less than 28 kg (163 mg tablets) and 28 kg to less than 35 kg (204 mg tablets). Tenofovir disoproxil (as fumarate) (Viread®) 33 mg/g granules are recommended as an option for use within NHS Wales in combination with other antiretroviral medicinal products for the treatment of HIV-1 infected paediatric patients, with NRTI resistance or toxicities precluding the use of first line agents, from 2 to < 6 years of age, and above 6 years of age for whom a solid dosage form is not appropriate. The choice of tenofovir disoproxil to treat antiretroviral-experienced patients with HIV-1 infection should be based on individual viral resistance testing and/or treatment history of patients.
Final Appraisal Recommendation (FAR)
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AWMSG Secretariat Appraisal Report (ASAR)
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Clinical Expert (CE) Summary
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