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topotecan hydrochloride (Hycamtin®)


Reference No. 316

Publication date:
20/03/2008


Appraisal information

topotecan hydrochloride (Hycamtin®) powder for concentrate for solution for infusion


Company: GlaxoSmithKline
BNF category: Malignant disease and immunosupression
NMG meeting date: 16/01/2008
AWMSG meeting date: 14/02/2008
   
   
Submission Type: Full Submission
Status: Superseded
Advice No: 0208
Ministerial ratification: 06/03/2008

Current Progress


Submission
received
NMG
meeting
AWMSG
meeting
Ministerial
Ratification

AWMSG advice

AWMSG ADVICE SUPERSEDED BY NICE GUIDANCE (TA183) NICE GUIDANCE ISSUED OCTOBER 2009 (Refer to NICE website for full guidance on NICE recommendations, including any specific restrictions on the use of the technology) Intravenous topotecan (Hycamtin®) is recommended for use within NHS Wales in combination with cisplatin, for the treatment of patients with carcinoma of the cervix recurrent after radiotherapy and for patients with Stage IVB disease. It is restricted for use in patients who are cisplatin-naïve. Topotecan (Hycamtin®) should only be initiated by specialists experienced in the treatment of cervical cancer. Topotecan (Hycamtin®) is not presently recommended for shared care.
Final Appraisal Recommendation (FAR)
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